Dustin Smith testified as a forensic toxicology expert about synthetic cannabinoids and AB Pinaca. His testimony addressed reported effects, the limits of the available research, and possible tolerance and withdrawal from chronic use.
Dustin Smith

South Carolina Law Enforcement Division forensic toxicology supervisor and chief toxicologist.
About
Dustin Smith testified on Day 14 after the court qualified him as an expert in forensic toxicology. On direct examination, he described synthetic cannabinoids, including AB Pinaca, their reported psychological and physical effects, and their potential presence in products known as Spice. He reviewed two State exhibits and gave general toxicology context rather than a person-specific opinion.
Defense counsel questioned Smith about AB Pinaca's legal status, the changing range of synthetic cannabinoids, and the limits of the research. Smith said the available half-life estimate came from an in-vitro study and that he knew of no studies showing how the human body interacts with AB Pinaca. He also distinguished between purchasers' expectation of a synthetic cannabinoid and uncertainty about the particular compound present.
On redirect, Smith explained why a laboratory half-life estimate could differ substantially in humans. He testified that published studies reported exacerbated effects for people with preexisting anxiety, depression, or mental illness, and that chronic use of a synthetic cannabinoid could produce tolerance and withdrawal after the drug was removed.
Key Points
The court qualified Smith as an expert in forensic toxicology, and he gave general testimony about synthetic cannabinoids, AB Pinaca, reported effects, and common methods of use. [1]
Smith agreed that the available AB Pinaca research was in vitro and did not establish how the drug interacts with the human body. [1]
Smith testified that synthetic cannabinoids may exacerbate effects for people with preexisting anxiety, depression, or mental illness, and that chronic use can lead to tolerance and withdrawal. [1]
Trial Record (3)
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